Yves Saint Laurent Opium Homme 100ml EDT Men Spray

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Thelwall, A. S. (1839). The iniquities of the opium trade with China; being a development of the main causes which exclude the merchants of Great Britain from the advantages of an unrestricted commercial intercourse with that vast empire. With extracts from authentic documents. London: Wm. H. Allen and Co.

Armero and Rapaport. The Arts of an Addiction. Qing Dynasty Opium Pipes and Accessories (privately printed, 2005) MacPherson, Duncan (1843). Two years in China. Narrative of the Chinese expedition, from its formation in April, 1840, to the treaty of peace in August, 1842. London, Saunders.

Opium contains 50 different alkaloid opiates. The most common metabolism of opiates is to be ultimately converted to morphine which is further converted to morphine-3,6-diglucuronide. 16 Opioids are metabolized vastly by the enzyme CYP 2D6 and any mutation in this kind of enzyme or coadministration with drugs that interfere with this enzyme may generate a change in the metabolism speed. 18 For years, because of this metabolism pathway, it was very hard to differentiate between illicit heroin users and involuntary exposure to poppy seeds. The original tests for this differentiations were based in the presence of morphine in urine without evidence of 6-monoacetylmorphine. Now it is known the presence of a glucuronide metabolite only in the consumption of heroin called ATM4G and this allows a clear differentiation of the consumption of illegal heroin and poppy seed ingestion. 6 Ballantyne, Jane C., and Jianren Mao. "Opioid Therapy For Chronic Pain". New England Journal of Medicine 349.20 (n.d.): 1943–1953. SocINDEX with Full Text. Web. November 3, 2011. Great Britain, India office (1922). The truth about Indian opium. [London] Printed by H.M. Stationery Off. Huxtable Ryan J.; Schwartz Stephen K. W. (2001). "The Isolation of Morphine—First Principles in Science and Ethics". Molecular Interventions. 1 (4): 189–191. PMID 14993340. a b c d Philip Robson (1999). Forbidden Drugs. Oxford University Press. p. 161. ISBN 978-0-19-262955-5.

Opium Factories of Bihar – Bihargatha". Bihargatha.in. Archived from the original on September 10, 2011 . Retrieved October 7, 2011. The production methods have not significantly changed since ancient times. Through selective breeding of the Papaver somniferum plant, the content of the phenanthrene alkaloids morphine, codeine, and to a lesser extent thebaine has been greatly increased. In modern times, much of the thebaine, which often serves as the raw material for the synthesis for oxycodone, hydrocodone, hydromorphone, and other semisynthetic opiates, originates from extracting Papaver orientale or Papaver bracteatum.

Creation Consumer Finance Ltd is authorised and regulated by the Financial Conduct Authority (Register no. 311518). Zhang, Sarah (January 9, 2019). "Why a Medieval Woman Had Lapis Lazuli Hidden in Her Teeth". The Atlantic . Retrieved May 10, 2020.

The standard medical use of opium persisted well into the 19th century. US president William Henry Harrison was treated with opium in 1841, and in the American Civil War, the Union Army used 175,000lb (80,000kg) of opium tincture and powder and about 500,000 opium pills. [1] During this time of popularity, users called opium "God's Own Medicine". [36] Professor Arthur C. Gibson. "The Pernicious Opium Poppy". University of California, Los Angeles. Archived from the original on October 20, 2013 . Retrieved February 22, 2014.Fueled in part by the 1729 ban on madak, which at first effectively exempted pure opium as a potentially medicinal product, the smoking of pure opium became more popular in the 18th century. In 1736, the smoking of pure opium was described by Huang Shujing, involving a pipe made from bamboo rimmed with silver, stuffed with palm slices and hair, fed by a clay bowl in which a globule of molten opium was held over the flame of an oil lamp. This elaborate procedure, requiring the maintenance of pots of opium at just the right temperature for a globule to be scooped up with a needle-like skewer for smoking, formed the basis of a craft of "paste-scooping" by which servant girls could become prostitutes as the opportunity arose. [47] Chinese diaspora in the West [ edit ] Use of opium as a cure-all was reflected in the formulation of mithridatium described in the 1728 Chambers Cyclopedia, which included true opium in the mixture. As the power of the Roman Empire declined, the lands to the south and east of the Mediterranean Sea became incorporated into the Islamic Empires. Some Muslims believe hadiths, such as in Sahih Bukhari, prohibits every intoxicating substance, though the use of intoxicants in medicine has been widely permitted by scholars. [16] Dioscorides' five-volume De Materia Medica, the precursor of pharmacopoeias, remained in use (which was edited and improved in the Arabic versions [17]) from the 1st to 16th centuries, and described opium and the wide range of its uses prevalent in the ancient world. [18]

John Richards (May 23, 2001). "Opium and the British Indian Empire" . Retrieved September 24, 2007. Morphine was first synthesised from opium in 1805 by a German chemist and was advertised as a new wonder medicine that was non-addictive and could even be used for the treatment of opium dependence. About 1850, the hypodermic syringe came into use and at that time people believed that smoking opium, rather than injecting opiates led to dependence. Thousands of soldiers in the American Civil War came home addicted to morphine given to them to ease the pain of their injuries. In 1874, again in Germany, heroin was first made from morphine – again it was advertised as non-addictive, this time as a substitute for morphine.Joyce A. Madancy (April 2004). "The Troublesome Legacy of Commissioner Lin" . Retrieved September 25, 2007. W. Travis Hanes III; Frank Sanello (February 1, 2004). The Opium Wars: The Addiction of One Empire and the Corruption of Another. Sourcebooks. pp.88–. ISBN 978-1-4022-5205-1. Both analgesia and drug addiction are functions of the mu opioid receptor, the class of opioid receptor first identified as responsive to morphine. Tolerance is associated with the superactivation of the receptor, which may be affected by the degree of endocytosis caused by the opioid administered, and leads to a superactivation of cyclic AMP signaling. [152] Long-term use of morphine in palliative care and the management of chronic pain always entails a risk that the patient develops tolerance or physical dependence. There are many kinds of rehabilitation treatment, including pharmacologically based treatments with naltrexone, methadone, or ibogaine. [153]