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Papilocare Vaginal Gel 21 canulas of 5 ml

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Hyaluronic acid niosomes): основното им свойство е повърхностно овлажняване на тъканите, придавайки им еластичност. Gel je indikovan za hidrataciju i obnavljanje sluzokože genitalne zone kojoj je potrebna posebna nega nakon određenih medicinsko-hirurških zahvata (na primer, nakon laserskog uklanjanja genitalnih kondiloma ili bradavica koje izaziva HPV). Niosomas de ácido láctico: Los niosomas son partículas microscópicas que encapsulan y liberan lentamente el ácido láctico, un componente clave para mantener el equilibrio del pH vaginal y prevenir el crecimiento de bacterias y otros microorganismos dañinos. Approximately 30% of Spanish women younger than 30 years are HPV carriers. 25 The likelihood of HPV infection decreases over time, from 47% between the ages of 15 and 19 years to 12% in women older than 45 years. 26 The HPV is a fundamental factor for the development of cervical cancer. 27 The World Health Organization has recently established the elimination of cervical cancer as a priority medium-term objective. 28 This trial aimed to explore whether treatment with Papilocare provides better results than the conventional watchful waiting strategy in improving low-grade cervical lesions, which are the first step in the natural history of cervical cancer. 29 Clearance of LSILs after a conservative approach is of approximately 59% within 2 years of the diagnosis. Nevertheless, the likelihood of progression of these lesions to a high-grade squamous intraepithelial lesion within 5 years is 12.7%. 30 In addition, treatments for cervical cancer severely compromise the reproductive health of women. In a systematic review of Cochrane, Kyrgiou et al. 31 demonstrated a higher baseline risk for prematurity in women with cervical intraepithelial neoplasia, which increased with excisional and ablative treatments. Therefore, the scenario is conflicting, as choosing an excisional or ablative approach for the treatment of LSILs can result in negative reproductive outcomes, but avoiding treatment and just monitoring the disease results in its progression to high-grade lesions in 12 of 100 women. The current recommendation in Spain also includes monitoring the disease. 32,33 However, based on the results of this present study, a novel strategy involving Papilocare has become available. The results of this treatment in the repair of low-grade lesions have demonstrated to significantly exceed those obtained with the watchful waiting approach (8 in 10 women achieved a normalization in their lesions). Formarea unei bariere de aparare in zona de transformare a colului uterin pentru a preveni riscul de patrundere a HPV.

Aplicati o canula cu doza unica in zona vaginala, de preferinta inainte de culcare. Apasati recipientul pentru a goli continutul acestuia si indepartati-l usor, fara clatire. If you find it helpful, you can squeeze out a small quantity of the gel and rub it around the tip of the tube to lubricate it.Persoane HPV pozitive cu leziuni (tratamentul leziunilor și prevenirea altora noi) - recomandat - Papilocare® Gel pentru zona genitală sản xuất trên dây truyền công nghệ hiện đại chuẩn châu âu cho tác động nhắm trúng đích, tăng cường sinh khả dụng của sản phẩm. care sunt deschise sau deteriorate trebuie aruncate. Aplicatorul este conceput pentru o aplicare mai ușoară Mod de depozitare: A se pastra la o temperatura cuprinsa intre 2 °C si 25 °C. A nu se lăsa la îndemâna copiilor.

Controlul si reepitelizarea zonei de transformare a colului uterin pentru a preveni riscul de aparitie a leziunilor (LSIL) cauzate de HPV.sarcină, înainte de a utiliza Papilocare, este necesar să consultați un medic, iar aplicarea ar trebui Papilocare se presenta en forma de gel en un tubo con aplicador, lo que facilita su aplicación y dosificación. El aplicador está diseñado para garantizar una distribución uniforme del gel en la zona vaginal, maximizando su eficacia y minimizando el riesgo de irritación o molestias. El envase de Papilocare contiene suficiente gel para un ciclo completo de tratamiento, y las instrucciones detalladas de uso se incluyen en el prospecto que acompaña al producto. Beneficios de Papilocare Otros beneficios relacionados: Además de tratar el VPH, Papilocare también puede ayudar a aliviar síntomas como irritación, picazón y sequedad vaginal. En este contexto, surge Papilocare, un innovador producto que ha demostrado ser eficaz en el tratamiento y prevención del VPH y sus complicaciones, especialmente en mujeres. Papilocare ha sido desarrollado para abordar específicamente las lesiones cervicales y vaginales causadas por el VPH, y su uso regular puede ayudar a prevenir la aparición de estas lesiones, mejorando la salud vaginal y reduciendo el riesgo de cáncer. Niosomi de β-glucan: datorita proprietatilor lor antioxidante mentin structura si functionalitatea naturala a pielii si a membranelor mucoase.

Gabriella, Kovács- Hain Zsuzsanna, Kapuvári Tamás, Tarjáni Rita, Dr. Jármi Hilda, Haris Éva, Ligeti Anna, Szarvas Zoltán, Vémi Zoltán A differential but nonsignificant trend in this parameter was observed between both groups, in such a way that it decreased in the treatment group (from a mean of 21.1 [SD = 8.8] at baseline, to a mean of 19.7 [SD = 9.0] at 3 months, and, finally, a mean of 19.0 [SD = 9.1] at 6 months) and increased in the control group (from a mean of 17.7 [SD = 7.2] at baseline, to a mean of 17.4 [SD = 6.3], and, finally, a mean of 20.7 [SD = 9.8] at 3 and 6 months, respectively). The number of patients reporting an improvement in perceived stress was higher at the 3-month (35 of 56 women [62.5%]) and 6-month visits (29 of 50 women [58.0%]) in the treatment group compared with the control group (15 of 31 women [48.4%] and 11 of 28 women [39.3%], respectively). Satisfaction With the Product and Therapeutic Adherence

Papilocare 21 (21x5ml)

membrana mucoasă a colului uterin și a vaginului (3 ml). După utilizare, aplicatorul trebuie aruncat. Aplicator El Virus del Papiloma Humano (VPH) es una infección de transmisión sexual común y potencialmente peligrosa que puede causar complicaciones graves, como el cáncer, si no se trata adecuadamente. Papilocare es un innovador producto que ha demostrado ser eficaz en el tratamiento y prevención del VPH y sus complicaciones, como las lesiones cervicales y vaginales. Numerosas mujeres han experimentado mejoras significativas en su salud y calidad de vida gracias al uso de Papilocare. A continuación, se presentan algunos testimonios de pacientes que han utilizado el producto con éxito:

The human papillomavirus (HPV) is one of the most common sexually transmitted infections and the most important etiological agent in cervical cancer. 1 Most HPV infections are asymptomatic and clear within 2 years without treatment. 2 Despite its low risk of progression to cervical cancer, many women experience negative emotional responses and even long-term psychological distress associated with an HPV-positive diagnosis and an abnormal cytology. 3, 4 When added to the fact that the conventional management strategy for this condition, especially in cases of low-grade lesion, is watchful waiting, the approach may become long and challenging for both the women and their physicians. Thus, a safe and nonsurgical treatment that can help repair the low-grade lesions and enhance viral clearance might be highly useful under these circumstances. 5 Papilocare (Procare Health, Valencia, Spain) is a Coriolus versicolor–based vaginal gel that combines ingredients boasting known properties, such as moisturizing, tissue regeneration, and balancing of the vaginal microbiota (hyaluronic acid, Asian centella, Aloe vera, and α-glucan oligosaccharide), 6, 7 with other ingredients with demonstrated positive effects on both HPV-dependent cervical lesions and HPV clearance ( C. versicolor, Azadirachta indica, and carboxymethyl-β-glucan). 8– 10 It has been hypothesized that HPV integration could be minimized by reducing the potential mitotic surface by re-epithelization. 11 On the other hand, the vaginal microbiota status plays a decisive role in the persistence or clearance of local infections. 12– 14 Improved re-epithelization and vaginal microbiota restoration have been observed in previous pilot studies involving the use of Papilocare in both asymptomatic, healthy women and HPV-positive patients with no cervical lesions. 15, 16 Moreover, a combination of C. versicolor and neem extract has shown to induce a local immune response in both in vitro and animal model studies 17– 19 hindering the oncogenic action of the HPV. Disponibilidad en nuestra farmacia online: Papilocare está disponible para su compra en nuestra farmacia online, ofreciendo comodidad y discreción a nuestros clientes. You can use Papilocare® at any time of day, but the gel is more likely to remain in place if you apply it just before bedtime. Prije primjene, lezite na leđa. Umetnite aplikator u rodnicu te pritisnite i istisnite sadržaj aplikatora. Izvadite aplikator iz rodnice dok i dalje pritiskate aplikator kako se ne bi natrag usisao upravo primijenjeni proizvod. Moguće je da mala količina gela ostane u aplikatoru. To ne znači da je primijenjena doza manja od preporučene jer iz aplikatora se oslobađa količina dovoljna za prekrivanje sluznice vrata maternice i rodnice (3 ml).hialurónico: Este ingrediente es conocido por sus propiedades hidratantes y regenerativas, ayudando a mantener la mucosa vaginal saludable y protegida. Women were randomized (1:1:1) into 3 treatment groups: scheme A, scheme B, or control (watchful waiting approach). Scheme A comprised using Papilocare once daily, preferably at bedtime, for 21 consecutive days followed by 7 days with no treatment throughout the first month, then an alternate-day therapy (except during the menstrual cycle) lasting up to 6 months. Scheme B was similar to scheme A except for the fact that the 21-day treatment/7-day rest period lasted for 3 months (instead of one) and that the alternate-day therapy lasted up to 3 months. Randomization was carried out using a centralized, computer-generated randomization list. Although sexual relations were not forbidden, the use of condoms was strongly recommended. The use of douches and vaginal deodorants was not allowed. Analyzed Variables

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